Fetal Growth
Publications
Systematic review of methodology used in ultrasound studies aimed at creating charts of fetal size. Ioannou C, Talbot K, Ohuma E, Sarris I, Villar J, Conde-Agudelo A et al. BJOG 2012, 119(12):1425-39.
The likeness of fetal growth and newborn size across non-isolated populations in the INTERGROWTH-21st Project: the Fetal Growth Longitudinal Study and Newborn Cross-Sectional Study. Villar J, Papageorghiou AT, Pang R, Ohuma EO, Cheikh Ismail L, Barros FC, Lambert A, Carvalho M, Jaffer YA, Bertino E, Gravett MG, Altman DG, Purwar M, Frederick IO, Noble JA, Victora CG, Bhutta ZA, Kennedy SH; International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st). Lancet Diabetes Endocrinol. 2014 Oct;2(10):781-92.
International standards for fetal growth based on serial ultrasound measurements: the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project. Papageorghiou AT, Ohuma EO, Altman DG, Todros T, Cheikh Ismail L, Lambert A et al. Lancet 2014, 384(9946):869-79.
International Estimated Fetal Weight Standards of the INTERGROWTH-21st Project. Stirnemann J, Villar J, Salomon LJ, Ohuma E, Lamber A, Victoria C G et al. Ultrasound Obstet Gynecol. 2016 Nov 2.
INTERGROWTH-21st standards for Hadlock's estimation of fetal weight. Stirnemann, J., Salomon, L.J. and Papageorghiou, A.T. (2020). Ultrasound Obstet Gynecol, 56: 946-948. https://doi.org/10.1002/uog.22000
Tables & Graphs
The graphs and charts are available with centiles or Z-scores (Standard deviation).
Head Circumference (HC) tables and charts:
Bi-Parietal Diameter (BPD) tables and graphs:
Abdominal Circumference (AC) graphs and charts:
Femur length (FL) graphs and charts:
Occipito-Frontal Diameter (OFD) tables and graphs:
Estimated Fetal Weight (EFW) tables and graphs:
These charts were updated in 2020 to use the Hadlock formula with three parameters, abdominal circumference, head circumference, and femur length. The 2016 formula only accounted for abdominal circumference and head circumference. The 2020 updated charts are the recommended charts to use for EFW.
Stirnemann, J., Salomon, L.J. and Papageorghiou, A.T. (2020). Ultrasound Obstet Gynecol, 56: 946-948. https://doi.org/10.1002/uog.22000
Calculators & Apps
These applications allows data to be entered manually so that the size of individuals can be compared to, and plotted graphically against, the international standards. In addition, large datasets can be imported directly into the application, which then calculates the respective centiles and z-scores based on the INTERGROWTH-21st Standards. The results can be exported for further analysis.
Head circumference, bi-parietal diameter, abdominal circumference, femur length, and occipito-frontal diameter for fetuses between 14+0 and 40+0 weeks' gestation.
Language options available: English, Portuguese, Spanish, French, Italian, Russian and Arabic.
The scripts for running the code in R are available:
If you are having any issues below is the user guide, troubleshooting guide and a sample file.